Study Provides New Estimates of Breast Cancer Risks Associated with HRT

Published: Nov. 9, 2020, 5 a.m.

SHR # 2617 :: Study Provides New Estimates of Breast Cancer Risks Associated with HRT - Dr. Yana Vinogradova, Ph.D. - A new study published by The BMJ today provides new estimates of the increased risks of breast cancer associated with use of different hormone replacement therapy (HRT) preparations in the UK. It confirms that HRT use is associated with increased risks of breast cancer, particularly for older women. However, it suggests that, for longer term HRT use, the increased risks are lower than those reported in a recent meta-analysis that combined the results of 24 studies. Today's study also shows a more noticeable decline in risks once HRT has stopped, compared with the same meta-analysis. The study discussed on today's show Use of hormone replacement therapy and risk of breast cancer: nested case-control studies using the QResearch and CPRD databases https://www.bmj.com/content/371/bmj.m3873