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Introduction: Hey Everyone, I am Brad Dieter, the COO of Macros Inc, a nutrition and fitness coaching company and this is MI Take, a podcast that discusses current events in nutrition, the business side of the health and fitness industry, and a little of everything in between. Let’s dive into it. 

Nutrition Insights: GLP-1 Drugs

What are they - either mimics of of natural GLP-1 or they are drugs that activate the receptors (GLP-1 receptors).

How do they work - augment insulin action and decrease glucagon. They also affect hunger and satiety through slowing digestion and affecting central nervous system.

What were the originally designed for - glucose control, 

How to they affect body weight -  primarily through hunger management. 

https://pubmed.ncbi.nlm.nih.gov/33977495/

https://jamanetwork.com/journals/jama/article-abstract/2777886

https://jamanetwork.com/journals/jama/article-abstract/2787907

Considerations for other diseases - however recently have been studied for kidney and cardiovascular protection as well as weight loss

Business Insights: The things behind running a 120+ person business that go unseen. 

What I am learning Today: You aren’t who you need to be until you become who you need to be.

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