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John Hennessy discusses his tenure as president of Stanford University and how he helped make it into an elite school: encouraging technological innovation on campus, working on ideas that push humankind forward and maintain academic excellence, and having one of the best athletic programs in the country. Hennessy notes that one key to Stanford’s success is building quality infrastructure around interdisciplinary themes in a cross-disciplinary space, making it possible to fire up smart people and challenge them with colleagues from varied backgrounds to develop innovative ideas and solutions to some of the world’s most complex problems.