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Isobel is a much longed for baby for Catherine and James, who want to spend as much time as possible with her on Bradford Infirmary's neo-natal unit. Being born at just 26 weeks old means she needs a good deal of mechanical intervention to survive and she has a dedicated nursing team to closely monitor her progress.

As Grace Dent hears, her chances of survival are good, but there is vigilance about possible longer term complications and in the early weeks she is very closely monitored. As tests continue, there is an added burden for her parents, who both work: Catherine's job takes her round West Yorkshire collecting and cremating dead animals and helping owners overcome their grief at losing much loved pets. She also runs a busy service putting down sick and dying horses.

Leaving Isobel on the unit whilst she works is hard to do, but all seems to be going well - and then there is a change. It is a testing time for Catherine, James and their Consultant, Dr Chris Day. He knows how difficult it is to predict who will do well and although girls born early tend to do better than boys, Isobel still faces challenges as she learns to breath and feed on her own. He and his team are dedicated to doing all they can to improve the chances of these very premature babies.

Producer: Sue Mitchell.