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Vinay Prasad is a practicing hematologist-oncologist who doubles as a \\u201cmeta-researcher,\\u201d studying the quality of medical evidence, health policy, and clinical trials. In this episode, Vinay discusses the differences in clinical treatment from the existing medical evidence, often leading to useless, or even harmful, outcomes for patients. With a focus in oncology, he takes a deep dive into the field\\u2019s structural problems, which include the disconnect between progress and funding, drug costs, and financial conflicts of interest. He concludes with his \\u201csix hallmarks of successful cancer policy\\u201d as a potential roadmap to sustained progress against cancer and a way to avoid repeating the policy and practice mistakes of the past.

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We discuss:

• Vinay\\u2019s background and unique perspective [3:15];
• Medical reversal\\u2014the disconnect between research findings and clinical applications in medicine [10:15];
• The uniquely challenging field of oncology [22:45];
• The importance of bedside manner with cancer patients [30:00];
• Structural problems in oncology\\u2014Problem #1: Huge costs for small improvements [37:00];
• Structural\\xa0problems in oncology\\u2014Problem #2: Medical reversal\\u2014when medical practices are adopted based on low levels of evidence [40:15];
• Structural\\xa0problems in oncology\\u2014Problem #3: Slow progress in cancer research (despite all the hype and propaganda) [45:00];
• Structural\\xa0problems in oncology\\u2014Problem #4: The burden of payment is not matched with those making treatment decisions [54:45];
• \\u201cNo-brainer\\u201d moves in oncology [1:06:45];
• \\u201cFool\\u2019s gold\\u201d treatments in oncology [1:09:30];
• The six hallmarks of successful cancer policy [1:16:00];
• Cancer policy hallmark #1: Independence [1:18:00];
• Cancer policy hallmark #2: Evidence [1:28:15];
• Cancer policy hallmark #3: Relevance [1:31:30];
• Cancer policy hallmark #4: Affordability [1:32:00];
• Cancer policy hallmark #5: Possibility [1:47:00];
• Cancer policy hallmark #6: Agenda [1:52:00];
• Tumor genome sequencing and liquid biopsies [1:54:30];
• Vinay\\u2019s clinical philosophy, being skeptical without being too contrarian, and practicing medicine without perfect information [2:03:30]; and
• More.

Learn more:\\xa0https://peterattiamd.com/

Show notes page for this episode: https://peterattiamd.com/VinayPrasad\\xa0

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