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In this episode, David Watkins, professor of pathology at George Washington University, shares how insights from his HIV and Zika virus research could apply to SARS-CoV-2 protection strategies. David introduces monoclonal antibodies as an intervention to prevent and treat COVID-19 infection, and also discusses how they could be used as a hedge to vaccine development. Additionally, David\\u2019s immunology tutorial explains the innate and adaptive immune systems and their differentiated responses to viral infection.

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We discuss:

• Background and current interest in immunology [4:30];
• Immunology 101\\u2014The innate and adaptive immune system [10:15];
• Defining antibodies, importance of neutralizing antibodies, and serology testing for COVID-19 [19:00];
• B cells\\u2014How they fight viruses, create antibodies, and fit into the vaccine strategy [25:00];
• T cells\\u2014Role in the adaptive immune system and ability to kill infected cells to prevent viral spread [36:15];
• Valuable lessons from HIV applied to SARS-CoV-2 [51:00];
• Lessons taken from the hepatitis C success story [1:01:30];
• Monoclonal antibodies, vaccines, and the most promising strategies for preventing and treating COVID-19 infection [1:04:45];
• COVID-19 vaccines in development [1:19:00];
• How David\\u2019s work with Zika virus informs his thinking on SARS-CoV-2 [1:25:20];
• Why a vaccine for COVID-19 doesn\\u2019t need to be perfect to be effective [1:27:45]; and
• More.

Learn more:\\xa0https://peterattiamd.com/

Show notes page for this episode: https://peterattiamd.com/davidwatkins

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