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Published: Oct. 29, 2020, 10:03 p.m.

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What is diabetes?

Diabetes is a condition where the body has problems to control blood sugar levels. There are two main types pf diabetes. In diabetes type 1, the body has an immune response to it's own beta cells and damages and destroy said cells. In diabetes type 2, is when not enough insulin is produced or the insulin that is produced does not work properly making the body's cell insulin resistant. Type 2 diabetes is manageable with the proper diet and exercise in most cases whereas type 1 diabetes requires that patients test their blood sugar levels regularly and administer insulin as necessary through an injection or a pump.

How can Stem cells help with diabetes?

Adipose derived mesenchymal cells, the cells we use at SCHI, are multipotent cells that can generate multiple cells lineages, including beta like cells. The cells are injected into the patient where they will allocate to the pancreas and either support the repair of beta cells in the patient or ideally differentiate into beta cells themselves which would then regulate the levels of insulin in the patient's body. Depending on the severity and the type of diabetes the patient has, the treatment, amount of cells and number of times the procedure is repeated and the results will vary.

We will continue developing our technology so we will hopefully be able to offer our patients the possibility of extracting biliary tree mesenchymal stem cells, which are already pancreatic progenitors which would see the efficacy of the treatment increase.

1. Stem Cell Therapy to Cure Type 1 Diabetes: From Hype to Hope

Stem Cells Transl Med. 2013 May; 2(5): 328–336. Published online  2013 Apr 9. doi: 10.5966/sctm.2012-0116. Preeti Chhabraand Kenneth L. Brayman

2. Regenerative Therapy of Type 1 Diabetes Mellitus: From Pancreatic Islet Transplantation to Mesenchymal Stem Cells

Stem Cells Int. 2016; 2016: 3764681.Published online 2016 Mar 7. doi:  10.1155/2016/3764681. Nadine E. Rekittke,Meidjie Ang, Divya Rawat, Rahul Khatri, and Thomas Linn

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