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Today’s question is: How to manage the comorbidities of PTSD?

Here is a summary of this episode:

• Screen for substance use and avoid prescription drugs like benzodiazepines. Desipramine and topiramate might help with comorbid alcohol use disorder.
• In PTSD-related psychosis, try an SSRI first. If that doesn’t help, add a second-generation antipsychotic like risperidone.
• Prescribe paroxetine with caution in women of childbearing potential.

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