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What You Need To Know About Psychedelics
- Psychedelics mimic serotonin and work as 5-HT2A agonists in the brain. They stimulate receptors largely localized in the association cortex.
- MDMA can help patients with PTSD by damping down emotional responses and so allowing processing of traumatic memories.
- In patients with treatment-resistant depression, psilocybin increased amygdala activity, which is the opposite effect of SSRIs.