Published: Oct. 30, 2018, 11:26 p.m.
Today’s question is: How to manage an agitated patient?
Here is a summary of this episode:
- Antipsychotics are the mainstay of treatment; addressing psychotic agitation as well as treating delirium. Haloperidol is best combined with a benzodiazepine, showing both high efficacy and low side effect profile.
- There are currently no FDA-approved oral regimens for agitation. However, there are orally disintegrating formulations of olanzapine, aripiprazole and risperidone. Asenapine is available in a sublingual formulation which requires more patient cooperation.
- Benzodiazepines have anxiolytic and sedating effects but can produce behavioral disinhibition and cognitive impairment in patients with dementia.