Intravenous Infusion - pdf

Published: Jan. 5, 2006, 4:47 a.m.

After completing the material in this chapter each student should:- * be able to draw the schemes and write the differential equations for a one compartment pharmacokinetic model after IV infusion administration * be able use the integrated equations for drug concentrations during and after an IV infusion administration to calculate parameter values and suitable dosing regimens including IV infusion alone, fast/slow IV infusion or infusion/bolus dosage regimens * be able to calculate kel and V from data collected after a single IV infusion * be able to define, use, and calculate the parameters: * * k0 (infusion rate constant) * * D (infusion duration)