After completing the material in this chapter each student should:- * be able to calculate ka using * * the method of Inspection * * the method of Residuals including * * * drawing the Cplate line * * * estimating the residual values * * * drawing the residual line (and possibly rescaling the time axis) * * the method of Wagner and Nelson and describe when each method may be most appropriate * be able to calculate F using plasma (AUC) or urine (U∞) data * understand the difference between absolute and relative bioavailability and be able to convert between these values