After completing the material in this chapter each student should:- * understand exponents and logarithms, algebraically and graphically * be able to use linear (Cartesian) and semi-log graph paper for the representation of data * be able to draw a 'best-fit' straight line through data on linear and semi-log graph paper *understand and able to use spreadsheets * understand differential and integral calculus * be able to write differential equations given a compartmental modeling scheme as a diagram or description * be able calculate the area under the plasma concentration versus time curve (AUC) using the linear trapezoidal rule