How to Optimize Fertility in Males & Females

Published: Jan. 23, 2023, 9 a.m.

b'I discuss the mechanisms by which human eggs and sperm are generated, the ovulatory/menstrual cycle, the conception process and overall fertility in males and females. I also explain how, regardless of whether you seek to conceive children, optimizing egg and sperm health is directly related to vitality and longevity. I cover nutritional, behavioral, supplemental, and medicinal approaches to optimizing egg and sperm health, the ovulatory/menstrual cycle and fertility. In addition, I explain lifestyle choices that greatly assist or harm fertility\\u2014several of which are very surprising. I provide science-based protocols for those trying to conceive children. The tools and principles I discuss can also improve overall vitality and longevity for everyone, regardless of age.\\xa0\\nNote: At the timestamp related to cumulative probability of pregnancy (2:01:30), I misspoke, my apologies. The data in this graph are correct but the \\u201c120%\\u201d is not.\\xa0\\nThe appropriate equation is 1-(1-p)^n where p is the probability of getting pregnant in a given cycle and n is the cycle number.\\xa0Therefore the equation for this scenario is\\xa01-(0.8^6).\\xa0Using the equation, cumulative probability over 6 cycles is 73.8% (rounded to 3 significant figures).\\xa0\\nThank you to our sponsors\\nAG1 (Athletic Greens):\\xa0https://athleticgreens.com/huberman\\nLMNT: https://drinklmnt.com/huberman\\nMomentous: https://www.livemomentous.com/huberman\\nTimestamps\\n(00:00:00) Fertility, Vitality & Longevity\\n(00:04:24) Sponsors: LMNT\\n(00:08:20) Eggs & Sperm, Genes, Fertilization\\n(00:18:28) Puberty: Gonadotropin Releasing Hormone (GnRH), Melatonin & Leptin\\n(00:23:38) Onset Trends of Puberty, Odors Effects\\n(00:27:44) Female Puberty, Luteinizing Hormone (LH), Follicle Stimulating Hormone (FSH)\\n(00:31:46) Sponsor: AG1\\n(00:36:34) Ovulatory & Menstrual Cycle\\n(00:40:36) Follicular Phase: Egg Maturation & Ovulation, FSH & Estrogen\\n(00:51:09) Luteal Phase: Progesterone & Estrogen, Menstruation\\n(00:58:14) Ovulation & Libido; Luteal Phase & Malaise; Individual Variability\\n(01:04:18) Sex Chromosomes, Sperm\\n(01:11:40) Tool: Testicular Temperature & Fertility\\n(01:17:22) Sperm Production, Seminal Fluid, Vasectomy\\n(01:24:07) Sperm Cells, Mitochondria & Motility, Intercourse Frequency & Fertilization\\n(01:28:31) Sperm Production, GnRH, FSH, LH & Testosterone\\n(01:36:21) Ejaculate Quality, Sperm Counts, Fertilization, Ectopic Pregnancy\\n(01:44:14) Tool: Sexual Intercourse Frequency & Fertilization\\n(01:53:24) Tools: Tracking Ovulation, Libido, Lubricants\\n(01:56:42) Fecundability: Egg Quality & Woman\\u2019s Age, Cumulative Pregnancy Rate\\n(02:08:17) Miscarriages, Chromosomal Abnormalities\\n(02:11:23) Female Fertility: Age, Follicle Testing & Anti-Mullerian Hormone (AMH) Testing\\n(02:18:51) Male Fertility: Sperm Analysis, Age\\n(02:24:52) Fertility & Hormone Analysis, Age\\n(02:29:07) Fertility Effects of Sleep, Cortisol/Stress, Cannabis/Nicotine & Alcohol\\n(02:42:40) Fertility, Sexually Transmitted Infections (STIs), Viral Infection & Cystic Fibrosis\\n(02:47:42) Tool: Testicular Temperature & Fertility\\n(02:51:26) Tool: Phones & Sperm Quality\\n(02:58:06) Deliberate Cold Exposure & Fertility, Testicular Temperature, Cortisol/Stress\\n(03:05:43) Fertility, Exercise & Mitochondrial Health; Intermittent Fasting\\n(03:14:46) Testosterone Replacement Therapy & Sperm Production; Supplements\\n(03:20:36) Sex Determination in Offspring, In Vitro Fertilization (IVF), Sperm Fractions\\n(03:32:23) Postcoital Female Position & Fertilization, Sperm Quality\\n(03:36:57) Cannabis & Sperm Motility, Libido, Pregnancy\\n(03:42:33) Acupuncture, Fertility & Pregnancy\\n(03:49:25) Fertility Supplements: L-Carnitine & Allicin, Coenzyme Q10\\n(03:56:18) Fertility Supplements: Inositol, Omega 3 Fatty Acids\\n(04:02:50) Supplements for Hormones: Tongkat Ali, Shilajit, Zinc\\n(04:13:02) Fertility & Prescription Medications\\n(04:16:44) Human Reproduction & Fertility\\n(04:20:12) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Momentous, Social Media, Newsletter'