Bypassing Surgery An Oral Pill for the Treatment of Morbid ObesityHasan CelikerXeno Biosciences

Published: Nov. 15, 2018, 9:11 a.m.

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Gastric bypass surgery is the most effective form of treatment for morbid obesity and a familiar term to most of us, but until recently, the underlying mechanism that makes it so successful has been largely misunderstood. Most people\\u2014including health professionals\\u2014attribute the weight loss that follows from this surgery to reduced stomach size and therefore reduced food intake and malabsorption, but the evidence is pointing elsewhere: to the changes in gut microbiota that occur after the surgery.


Hasan Celiker is the founder and chief executive officer of Xeno Biosciences, a company that\\u2019s using what they\\u2019ve learned about the effectiveness of gastric bypass surgery to develop an alternative and significantly less invasive form of treatment for obesity: an oral pill that mimics the changes in gut microbiota that occur after the surgery, allowing for weight loss and a significant reduction in conditions associated with obesity, such as diabetes and fatty liver disease.


Celiker delves into the details of digestive mechanisms, the differences between aerobic and anaerobic bacteria and the role of each in the microbiome, how and where in the body Xeno Bioscience\\u2019s pill takes effect, and the metabolic changes brought about by both the pill and the surgery. Hit play and visit\\xa0xenobiosciences.com\\xa0to learn more.\\xa0


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