Podcasts Health & Fitness Medicine FoundMyFitness #081 The Anabolic Potential of Omega-3 Fatty Acids | Chris McGlory, PhD

#081 The Anabolic Potential of Omega-3 Fatty Acids | Chris McGlory, PhD

Published: July 3, 2023, 3:17 p.m.

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Dr. Chris McGlory is an assistant professor at Queen\'s University in Kingston, Ontario, Canada. Known for his work in the field of muscle physiology and aging, Dr. McGlory\'s research focuses on elucidating the molecular mechanisms underlying muscle protein synthesis and degradation, with a particular emphasis on the roles that omega-3 fatty acids play in maintaining muscle health in older adults.

In this episode, we discuss:

  • (00:00)\\xa0Introduction
  • (05:50)\\xa0Start of interview
  • (13:03) Why atrophy is worse for the old than the young
  • (15:23) Can dietary protein prevent atrophy?
  • (17:35) Why reduced movement can insidiously mimic short-term immobilization
  • (22:51)\\xa0The disability threshold \\u2014 when atrophy may actually be deadly
  • (24:58)\\xa0Does high-dose omega-3 hold the key to fighting atrophy? (5g/day)
  • (28:35)\\xa0Does omega-3 help muscle respond more optimally to low protein?
  • (41:37)\\xa0Why omega-3 must be preloaded for 4 to 6 weeks
  • (44:20)\\xa0Why omega-3 trials have conflicting results
  • (50:16) Does omega-3 enhance strength?
  • (52:42)\\xa0Sex differences in gaining mass and strength
  • (54:46)\\xa0Improvements in gait speed and balance (muscle performance / physical performance battery)
  • (55:49)\\xa0How to act on mixed evidence \\u2014 and should we?
  • (58:17)\\xa0Why omega-3 may reduce frailty in old age
  • (1:01:59)\\xa0Why the anabolic mechanisms are counterintuitive (going beyond the canonical anti-inflammatory role of omega-3)
  • (1:07:42)\\xa0Do omega-3s boost tired, dysfunctional mitochondria?
  • (1:15:16)\\xa0Why we need an "omega-3 index" for muscle
  • (1:18:52)\\xa0Why the inflammation from cancer wastes muscle
  • (1:20:38)\\xa0Does omega-3 reduce atrophy from cancer cachexia?

Watch this episode on YouTube

Show notes are available by clicking here

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