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George Church, Ph.D. is a professor of genetics at Harvard Medical School and of health sciences and technology at both Harvard and the Massachusetts Institute of Technology. Dr. Church played an instrumental role in the Human Genome Project and is widely recognized as one of the premier scientists in the fields of gene editing technology and synthetic biology.\\xa0

In this episode, we discuss:

• (00:00) Introduction to Dr. George Church
• (07:13)\\xa0History of the Human Genome Project
• (15:20)\\xa0Manufacturing cell phones (with biology)
• (17:34)\\xa0Genome Project-Write
• (20:03)\\xa0Writing a human Y chromosome (from scratch)
• (20:48)\\xa0What if you could eliminate viral disease?
• (22:51)\\xa0De-extinction and reinstating lost traits and genes
• (27:06)\\xa0The Vertebrate Genomes Project
• (29:47)\\xa0AlphaFold and other AI tools
• (41:27)\\xa0CRISPR vs. Base Editing (emerging tools of genetic engineering)
• (49:40)\\xa0Why multiplex editing will change the world
• (52:18)\\xa0Molecular flight recorder
• (53:31)\\xa0Preventing viral spillover and enhancing livestock
• (57:40)\\xa0PCSK9 gene therapy for cholesterol
• (1:00:30)\\xa0Is aging an evolved program?
• (1:05:21)\\xa0Treating aging with a combination gene treatment
• (1:09:04)\\xa0Does animal research help us understand human aging?
• (1:11:40)\\xa0Human organoids as a model and therapeutic
• (1:13:34)\\xa0Could engineered transplant organs become better than the originals?
• (1:16:17)\\xa0Embryo editing controversy
• (1:28:41)\\xa0Gene editing for space travel
• (1:30:40)\\xa0Can synthetic biology alleviate poverty?
• (1:34:07)\\xa0Is in vitro fertilization and embryo selection practically similar to editing?
• (1:39:12)\\xa0The occasional cost of brilliance
• (1:45:45)\\xa0Eradicating disease with Gene Drive
• (1:48:55)\\xa0Technologies to solve Lyme disease
• (1:51:57)\\xa0Dr. Church\'s experience with narcolepsy as a bridge to creative insights
• (2:00:42)\\xa0Why George encoded his book in DNA

Watch this episode on YouTube

Show notes are available by clicking here

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