BROADCASTS.com

b'

Eric M. Verdin

Eric M. Verdin, M.D. is the fifth president and chief executive officer of the Buck Institute for Research on Aging and is a professor of Medicine at UCSF.

Dr. Verdin\'s laboratory focuses on the role of epigenetic regulators in the aging process, the role of metabolism and diet in aging and on the chronic diseases of aging, including Alzheimer\\u2019s, proteins that play a central role in linking caloric restriction to increased healthspan, and more recently a topic near and dear to many of you, ketogenesis. He\'s held faculty positions at the University of Brussels, the NIH and the Picower Institute for Medical Research.

\\xa0In this episode, you\'ll discover:

• (00:00) Introduction
• (07:32)\\xa0Interventions to prolong lifespan
• (10:42)\\xa0The role of insulin pathways in aging
• (16:25)\\xa0HDAC inhibition by ketones
• (27:52)\\xa0Protein activates mTOR & IGF-1
• (30:28)\\xa0PPAR-alpha activation facilitates benefits of a ketogenic diet
• (35:28)\\xa0What biomarkers can predict aging?
• (39:38)\\xa0Cellular NAD+ levels decrease with age\\xa0
• (52:47)\\xa0Ketogenic diet safety\\xa0
• (56:07)\\xa0Intermittent fasting as an alternative to a keto diet

If you\\u2019re interested in learning more, you can read the full show notes here.

Join over 300,000 people and get the latest distilled information on ketogenic diet & longevity straight to your inbox weekly: https://www.foundmyfitness.com/newsletter

Become a FoundMyFitness premium member to get access to exclusive episodes, emails, live Q+A\\u2019s with Rhonda and more: https://www.foundmyfitness.com/crowdsponsor