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Dr. Judith Campisi is a professor of biogerentology at the Buck Institute for Research on Aging and a co-editor in chief of the Aging Journal.

As an expert on cellular senescence, the discussion involves a lot of talk\\xa0about aging and cancer, where senescence plays a very important fundamental role. What are some of the strategies we might use in the future to prevent senescent cells? What causes them in the first place?\\xa0

In this episode, you\\u2019ll discover:\\xa0

• (00:00)\\xa0Introduction
• (05:12)\\xa0Fundamental molecular and cellular processes of aging
• (13:19)\\xa0What is senescence and why did we evolve this cellular function?\\xa0
• (24:09)\\xa0The difference between lifespan and healthspan
• (30:32)\\xa0DNA damage and mitochondrial dysfunction promote senescence\\xa0
• (35:45)\\xa0Prolonged fasting suppresses senescent cells and stimulates new cell growth
• (47:30)\\xa0Exercise extends healthspan, partially by lengthening telomeres
• (54:03)\\xa0Consumer tests for DNA damage and cellular senescence
• (59:58)\\xa0NAD+ boosters, fasting mimetics, and aging in non-human animals

If you\\u2019re interested in learning more, you can read the full show notes here.

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