#029 Jed Fahey, Sc.D. on Isothiocyanates, the Nrf2 Pathway, Moringa & Sulforaphane Supplementation

Published: Jan. 6, 2017, 4:07 a.m.

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Dr. Jed Fahey is a multi-decade veteran of isothiocyanate research and is the director of the Cullman Chemoprotection Center at Johns Hopkins University.

In this episode, you\'ll discover:

  • (00:00)\\xa0Introduction
  • (03:44)\\xa0What is sulforaphane?
  • (10:25)\\xa0The NRF2 pathway, a master regulator of antioxidants
  • (14:22)\\xa0Cruciferous vegetables are rich sources of sulforaphane
  • (20:39)\\xa0Does cooking broccoli destroy sulforaphane?\\xa0
  • (26:00)\\xa0Sulforaphane supplements vary widely in quality
  • (36:41)\\xa0Antibiotics wipe out sulforaphane-producing bacteria in the gut
  • (46:44)\\xa0Managing Helicobacter pylori growth with a sulforaphane-rich diet
  • (56:15)\\xa0Sulforaphane reduces inflammation, but does it extend lifespan?
  • (01:11:31)\\xa0The therapeutic potential of sulforaphane for autism spectrum disorders, Alzheimer\'s disease, and schizophrenia
  • (01:22:44)\\xa0Research challenges and clinical trials
  • (01:30:51)\\xa0Is sulforaphane an anti-depressant?
  • 01:34:50 - Moringin from moringa may be an alternative to sulforaphane with similar bioaction
  • (01:53:55)\\xa0How to maximize sulforaphane conversion
  • (02:13:27)\\xa0Testing the anticancer power of sulforaphane\\xa0

If you\\u2019re interested in learning more, you can read the full show notes here.

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