#002 Dr. George Brooks on Lactate Shuttle Theory, Relevance for Traumatic Brain Injury, and More

Published: Dec. 2, 2014, 11:45 p.m.

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Dr. George A Brooks

Dr. George A Brooks, an expert in exercise physiology and lactate metabolism. Lactate, a once demonized molecule thought to form lactic acid and become a dead-end toxic metabolite, has been vindicated by the work of Dr. Brooks, his colleagues, and others.\\xa0

In this episode, we discuss...\\xa0

  • (00:00)\\xa0Introduction
  • (01:40)\\xa0Dr. Brooks\\u2019 experience as an athlete inspired his research on lactate
  • (06:50)\\xa0Lactate and its relationship to muscle fatigue is misunderstood
  • (09:10)\\xa0Adaptations to exercise improve mitochondrial functioning and lactate metabolism
  • (14:14)\\xa0How to use lactate threshold training to improve performance
  • (23:49)\\xa0Lactate improves brain health and cognitive function\\xa0
  • (26:45)\\xa0Lactate improves outcomes of traumatic brain injury via metabolism
  • (30:00)\\xa0Lactate spares glucose, increasing antioxidants such as glutathione
  • (42:50)\\xa0Early lactate administration following a traumatic brain injury is necessary, but challenging
  • (48:20)\\xa0Lactate from exercise improves Parkinson\'s disease\\xa0
  • (55:00)\\xa0Brain metabolism following traumatic brain injury

If you\\u2019re interested in learning more, you can read the full show notes here.

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