Podcasts Health & Fitness Medicine FOAMcast - An Emergency Medicine Podcast Fluoroquinolones and Aortic Pathology

Fluoroquinolones and Aortic Pathology

Published: Jan. 31, 2019, 11:59 a.m.

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The US Food and Drug Administration (FDA) recently released another warning for fluoroquinolones, this time regarding aortic dissection and aneurysm.\\xa0 We review the evidence behind this warning, including the following studies:

Lee CC\\xa0\\xa0Risk of Aortic Dissection and Aortic Aneurysm in Patients Taking Oral Fluoroquinolone. JAMA Intern Med. 2015;175(11):1839-47.

Lee CC\\xa0Oral Fluoroquinolone and the Risk\\xa0of\\xa0Aortic Dissection. J Am Coll Cardiol. 2018;72(12):1369-1378.

Pasternak B\\xa0Fluoroquinolone use and risk of aortic aneurysm and dissection: nationwide cohort study. BMJ. 2018;360:k678.

We then review the ACEP clinical policy on aortic dissection\\xa0covering risk scores, d-dimers, and management of aortic dissection

Thanks for listening!

Jeremy Faust and Lauren Westafer

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