COVIDcast - Tocilizumab

Published: Oct. 25, 2020, 2:30 a.m.

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We interrupt our normal FOAMcast episodes to bring you updates from COVID-19. *Our understanding of COVID-19 is rapidly developing and this may be out of date in days/weeks. So, check back for updates/fact check what you hear*

Monoclonal antibodies have received significant attention over the past month and we previously podcasted on antibodies that target SARS-CoV-2. In this episode, we review several recent studies on a different "mab", tocilizumab,\\xa0 which targets inflammation mediated by interleukin-6 that is overly ramped up.\\xa0

We review:

Stone et al \\xa0( RCT)

Hermine et al (RCT)

Salvarani et al. (RCT)

STOP-COVID (observational)

Show notes (references/graphics):\\xa0FOAMcast.org

Thanks for listening,
Lauren Westafer and Jeremy Faust

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