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Episode 2495 - On this Friday's show Vinnie Tortorich speaks with Dr. Cate Shanahan about her new book about oxidative stress, the downside of working against nature, and more. https://vinnietortorich.com/2024/05/working-against-nature-dr-cate-shanahan-episode-2495 PLEASE SUPPORT OUR SPONSORS YOU CAN WATCH ALL THE PODCAST EPISODES ON YOUTUBE - Root Causes of Oxidative Stress Cate first noticed issues in pro basketball players. (2:30) What she found out was a symptom of metabolic problems. Dr. Shanahan was one of the early voices who emphasized the toxicity of seed oils. (6:00) She explains how she started paying attention to seed oils. Her background in biochemical engineering transitioned to medical school; however, her personal medical issues led her to a deep dive into health. Her book \u201cDark Calories\u201d is available in Vinnie\u2019s Book Club . She explains the meaning behind the name. (13:00) Metabolic disease is rampant. Being \u201changry\u201d is a sign of insulin resistance, which is a stage of metabolic disease. New standards of testing need to happen; she\u2019s a big believer in using the HOMA-IR testing. They discuss oxidative stress and seed oils and how they are included in many things. (20:00) She defines what she has named as \u201cThe Hateful 8.\u201d It\u2019s a similar effect of oxidation as cigarette smoking. Vinnie asks her about her list called the \u201cDelightful Dozen.\u201d (27:00) She hopes to get more doctors on board in expanding the message regarding various oils and the effects of oxidative stress. (35:00) Free radical particles are caused by oxidative stress; vegetable oils are \u201coxidative stress in a bottle.\u201d (42:30) Empty calories from processed foods and sugars can cause them too. She also challenges the use of protein powders. (46:00) Respecting Nature and how it works is important; trying to \u201coutsmart\u201d nature is a dead-end game. (54:00) The energy model of insulin resistance has to do with your body not being able to use its body fat as fuel. (56:00) Her book \u201cDark Calories\u201d provides information that can help you reduce cravings while you heal from insulin resistance. (57:00) Working Against Nature Vinnie asks Cate how can people do better. (59:00) She provides several practical food suggestions. \u201cRoot cause\u201d knowledge will help you. They pivot to cholesterol. (1:04:00) Cholesterol is a nutrient\u2014it is a building block of cells and hormones. The egg is the most complete package of nutrients you can get. There are plenty of untruths in the \u201cGame Changers\u201d film; they elaborate. (1:06:00) You need to know what is both good and bad about the medical system. The conversation on nutrition is the American College on Lifestyle Medicine, which is a Seventh-Day Adventist group promoting their religious stance on eating and lifestyle. (1:10:00) Vinnie asks Cate\u2019s take on GLP-1s. (1:14:00) She is against them for many reasons; the first one is that those drugs are working against Nature. Acute muscle loss is happening to patients on drugs like Ozempic; remember your heart is a muscle. She lists other concerns she has about them. There's a new NSNG\xae Foods promo code you can use! (53:00) The promo code ONLY works on the NSNG\xae Foods website, NOT on Amazon. Vinnie's new documentary "Dirty Keto" is out! Go to to get it at ! [the_ad id="20253"] PURCHASE BEYOND IMPOSSIBLE (2022) The documentary launched on January 11! Order it TODAY! This is Vinnie\u2019s third documentary in\xa0just over\xa0three years. Get it now on Apple TV (iTunes) and/or Amazon Video! Link to the film on Apple TV (iTunes):\xa0 Then, Share this link with friends, too! It's also now available on Amazon (the USA only for now)!\xa0 Visit my new Documentaries HQ to find my films everywhere: REVIEWS: Please submit your REVIEW after you watch my films. Your positive REVIEW does matter! FAT: A DOCUMENTARY 2 (2021) Visit my new Documentaries HQ to find my films everywhere: Then, please share my fact-based, health-focused documentary series with your friends and family. The more views, the better it ranks, so please watch it again with a new friend! REVIEWS: Please submit your REVIEW after you watch my films. Your positive REVIEW does matter! FAT: A DOCUMENTARY (2019) Visit my new Documentaries HQ to find my films everywhere: Then, please share my fact-based, health-focused documentary series with your friends and family. The more views, the better it ranks, so please watch it again with a new friend! REVIEWS: Please submit your REVIEW after you watch my films. Your positive REVIEW does matter!