Treating Schizophrenia by Mitigating Peripheral Side Effects from Existing Antipsychotics with Dr. Stephen Brannan Karuna Therapeutics

Published: April 7, 2021, 4:40 p.m.

Dr. Stephen Brannan, Chief Medical Officer, Karuna Therapeutics discusses the need for creating and delivering transformative medicines for people living with psychiatric and neurological conditions particularly schizophrenia. Pairing the muscarinic agonist with a pan-cholinergic antagonist that does not cross into the central nervous system, KarXT is mitigating the peripheral side effects like weight gain and sedation but still retaining the benefits from muscarinic agonist.

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Karuna Therapeutics