Podcasts Health Dr. Howard Smith Oncall Methylprednisolone Conquers CoVid Better Than Dexamethasone

Methylprednisolone Conquers CoVid Better Than Dexamethasone

Published: Feb. 13, 2021, 9:14 p.m.

 

Vidcast:  https://youtu.be/Gw9tMwVXpII

 

Methlprednisolone, SoluMedrol, is 42% more likely to save a critically ill CoVid patients than dexamethasone, Decadron.  Critical care specialists at University of Southern California followed 262 ICU CoVid patients.

 

The 83 patients receiving Decadron in addition to critical respiratory care  enjoyed a 36% lower mortality rate.  The 104 patients given SoluMedrol though had a 61% lower mortality rate.

 

Decadron has become standard therapy for severely ill CoVid patients, but the investigators remind us that SoluMedrol has long been the clinically preferred anti-inflammatory drug for those with severe respiratory disease.  In this study, this potent steroid over a short course saves the day.

 

https://www.medrxiv.org/content/10.1101/2021.02.03.21251088v1.full.pdf

 

#steroids #dexamethasone #methylprednisolone #ventilator