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Brain tissue exposed to explosive shockwaves suffer a 60-80% decline in proteins necessary to maintain working connections and information flow between brain cells.  Neuroscientists at the University of North Carolina collaborated with colleagues at the US Army Research Laboratory to test the effects of select battle shockwave trauma on hippocampal brain tissues kept alive in tissue culture.

The investigators propose that these types of combat blast exposures not only interrupt vital information flow within the brain, but they also lead to degenerative changes characteristic of pre-dementia including pre-Alzheimer’s.  These finding correlate with clinical findings in blast-exposed soldiers who demonstrate confusion, cognitive deficits, and memory loss.

https://onlinelibrary.wiley.com/doi/10.1111/bpa.12936

#explosion #military #ptsd #dementia #alzheimers