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The Derms and Conditions Podcast had a very successful year in 2022! Many discussions took place covering a wide range of topics in dermatology, including new published information, treatments, technologies, medications, and practical tips to improve the overall performance of your practice. Derms and Conditions wraps up the year by summarizing valuable insights and information for dermatology practitioners. Host James Q. Del Rosso, DO, explains the value of occasionally going back and listening to past episodes as some "pearls" always seem to emerge that were missed during the initial listening of the podcast. Some of the greatest hits from episodes released in 2022 were highlighted. This includes perspectives on managing actinic keratoses (Dr. Mark G. Lebwohl, MD), a review of the "STOP" approach to rosacea which incorporates effective patient collaboration (Dr. Julie C. Harper, MD), ways to integrate aesthetic and cosmetic dermatology into your medical dermatology practice (Dr. Patricia K. Farris, MD), and a discussion of how tumescent anesthesia can expand the range of procedures that dermatologists can effectively and safely perform in the office (Dr. Sandra Lee, MD). Many thanks for listening and we look forward to Season 3 in 2023.