ALS Untangled Series: Ep. 13 – Antiretrovirals

Published: Dec. 20, 2018, 12:51 p.m.

Several observations suggest that retroviruses might be able to kill motor neurons, causing forms of ALS. Here we review these data, focusing on the theory that reactivation of an "endogenous" retrovirus we all have hiding in our genes called Herv-K might cause some cases of sporadic ALS. We examine drugs that attack retroviruses as potential treatments for patients with ALS.