Dr. Ted Burns interviews Drs. Jessica Nance and Andrew Mammen about their paper Diagnostic evaluation of rhabdomyolysis from the June 2015 issue of Muscle and Nerve. This podcast focuses on the clinical presentation and acquired causes which can include substance abuse, medication or toxic exposures, electrolyte abnormalities, endocrine disturbances, and autoimmune myopathies. For the article in Muscle and Nerve refer to Muscle Nerve 51: 793-810, 2015.