Podcasts general Professor Salvador Moncada - Audio
Professor Salvador Moncada - Audio

Professor Salvador Moncada - Audio

24 episodes

From 1975 to 1995, Professor Moncada worked at the Wellcome Research Laboratories, first as Head of Prostaglandin Research and then as Director of Research. He described the structure of prostacyclin, which acts as an effective vasodilator and also prevents blood platelets from clumping. In 1980 came the discovery by Robert Furchgott of ‘endothelium-derived relaxing factor’ (EDRF) which causes smooth muscle in the vessel walls to relax. Moncada and his team showed that EDRF was, in fact, Nitric oxide, which has since become appreciated as a neurotransmitter, a modulator of inflammation and a sensor of cellular distress as well as a regulator of vessel tone. Nitric oxide is both the target and effector of a range of compounds now being used for the treatment of cardiovascular and rheumatic diseases. Professor Moncada was appointed Director of the Wolfson Institute for Biomedical Research at University College in 1995. He has won numerous awards from the international scientific community including a Dart/NYU Biotechnology Achievement Award, the Prince of Asturias Scientific and Technological Research Award and the Dr AH Heineken Prize for Medicine from the Royal Netherlands Academy of Arts and Science.

Podcasts

1. Growing up in Central America

Published: June 24, 2009, 9:50 a.m.
Duration: 2 minutes 50 seconds

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23. Mitochondria: new ideas about the way cells use energy sources

Published: April 24, 2009, 2:58 p.m.
Duration: 3 minutes 50 seconds

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22. Mitochondria: nitric oxide as modulator of oxygen consumption

Published: April 24, 2009, 2:57 p.m.
Duration: 3 minutes 48 seconds

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6. Blood platelet function - why aspirin causes bleeding

Published: April 24, 2009, 2:57 p.m.
Duration: 2 minutes 39 seconds

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4. Prostaglandins and Aspirin - the importance of bioassay

Published: April 23, 2009, 12:46 p.m.
Duration: 4 minutes 42 seconds

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7. Discovering thromboxane synthase, and a new enzyme

Published: April 23, 2009, 12:35 p.m.
Duration: 3 minutes 45 seconds

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3. Professor Salvador Moncada - Starting work in John Vane's_laboratory, 1971

Published: April 23, 2009, 12:34 p.m.
Duration: 2 minutes 7 seconds

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24. Wellcome's important characteristics

Published: April 23, 2009, 12:32 p.m.
Duration: 2 minutes 45 seconds

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21. Septic shock

Published: April 23, 2009, 12:31 p.m.
Duration: 4 minutes 47 seconds

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20. Inflammation, rheumatoid arthritis and tissue damage

Published: April 23, 2009, 12:31 p.m.
Duration: 4 minutes 11 seconds

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19. Nitric oxide, erectile dysfunction and Viagra

Published: April 23, 2009, 12:31 p.m.
Duration: 2 minutes 15 seconds

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18. Ethical matters ethical editor on the Journal of Physiology

Published: April 23, 2009, 12:31 p.m.
Duration: 1 minute 28 seconds

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17. Nitric oxide as regulator of blood pressure and blood flow

Published: April 23, 2009, 12:30 p.m.
Duration: 3 minutes 40 seconds

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16. Nobel Prize, 1988

Published: April 23, 2009, 12:30 p.m.
Duration: 1 minute 30 seconds

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15. The biochemical pathway of nitric oxide in the brain

Published: April 23, 2009, 12:30 p.m.
Duration: 2 minutes 57 seconds

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14. Determining how nitric oxide is made

Published: April 23, 2009, 12:29 p.m.
Duration: 3 minutes 37 seconds

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13. Measuring_nitric_oxide_produced_by_endothelial_cells

Published: April 23, 2009, 12:29 p.m.
Duration: 3 minutes 6 seconds

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12. Discovering that EDRF is nitric oxide (NO), 1986

Published: April 23, 2009, 12:29 p.m.
Duration: 2 minutes 53 seconds

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11. Discovery of EDRF (Endothelium Derived Relaxing Factor) 1980

Published: April 23, 2009, 12:28 p.m.
Duration: 2 minutes 28 seconds

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10. Structure of prostacyclin, 1976 - Nobel Prize, 1982

Published: April 23, 2009, 12:28 p.m.
Duration: 3 minutes 23 seconds

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9. Homeostatic functioning of the blood vessel wall

Published: April 23, 2009, 12:28 p.m.
Duration: 2 minutes 43 seconds

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8. The Prostacyclin Discovery

Published: April 23, 2009, 12:27 p.m.
Duration: 2 minutes 40 seconds

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5. Group_leader_at_Wellcome_Research_Laboratory

Published: April 23, 2009, 12:27 p.m.
Duration: 1 minute 27 seconds

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2. Medical school and expulsion from El Salvador

Published: April 23, 2009, 12:26 p.m.
Duration: 2 minutes 59 seconds

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