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In this \u201cAsk Me Anything\u201d (AMA) episode, Peter and Bob dive deep into cancer screening, including why it\u2019s important, what you need to know about a test, and Peter\u2019s approach with patients. They specifically discuss various screening methods, explain important terms like sensitivity and specificity, and how layering and stacking different tests in tandem can improve predictive values. They conclude with a discussion on one of the more exciting screening tools, diffusion-weighted MRI, and how it\u2019s changing the cancer screening landscape.

If you\u2019re not a subscriber and listening on a podcast player, you\u2019ll only be able to hear a preview of the AMA. If you\u2019re a subscriber, you can now listen to this full episode on your\xa0private RSS feed\xa0or on our website at the\xa0AMA #25 show notes page. If you are not a subscriber, you can learn more about the subscriber benefits\xa0here.

We discuss:

• The importance of cancer screening [1:15];
  
• Cancer screening terms: sensitivity, specificity, false positives, and false negatives [8:25];
  
• Cancer screening terms: positive and negative predictive value [17:00];
  
• Improving predictive value by layering tests, and the predictive values of mammograms [25:45];
  
• How smoking impacts the predictive value of cancer screening [30:45];
  
• Liquid biopsies for ruling out cancer and the blind spots of common cancer screening tests [33:00];
  
• The difference between cancer originating from inside versus outside the body [41:15];
  
• How diffusion-weighted MRI is changing cancer screening [45:15];
  
• Summary of Peter\u2019s approach to cancer screening [53:45]; and
  
• More.

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Show notes page for this episode: https://peterattiamd.com/ama25\xa0

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