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Evolution of The Carnivore Diet, Issues on Keto Diet: Maybe Electrolyte Imbalance?, Weird Reaction To Beef & Lamb?, Do All Cells React to Light?, Electrolyte/Magnesium Sensitivity?

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Show Notes:

News topic du jour:

Obesity and disease tied to dramatic dietary changes

The \'mismatch hypothesis\' argues that our bodies evolved to digest the foods that our ancestors ate, and that human bodies will struggle and largely fail to metabolize a radically new set of foods. This intuitive idea is hard to test directly, but the Turkana, a pastoralist population in remote Kenya, present a natural experiment: genetically homogenous populations whose diets stretch across a lifestyle gradient from relatively \'matched\' to extremely \'mismatched\' with their recent evolutionary history.

Enter the Turkana -- a subsistence-level, pastoralist population from a remote desert in northwest Kenya. In the 1980s, an extreme drought coupled with the discovery of oil nearby led to rapid transformation of the region. Large segments of the population abandoned their nomadic lifestyle, some to live in villages and others in cities. Traditional Turkana still rely on livestock -- dromedary camels, zebu cattle, fat-tailed sheep, goats, and donkeys -- for subsistence, while Turkana living in cities have switched to diets that are much higher in carbohydrates and processed foods . This is a trend that is widely observed across the world, a result of increasing globalization, even in remote communities.

"We realized that we had the opportunity to study the effect of transitioning away from a traditional lifestyle, relying on almost 80% animal byproducts -- a diet extremely protein-rich and rich in fats, with very little to no carbohydrates -- to a mostly carbohydrate diet," said Julien Ayroles, an assistant professor of ecology and evolutionary biology and LSI who is the senior researcher on the new paper. "This presented an unprecedented opportunity: genetically homogenous populations whose diets stretch across a lifestyle gradient from relatively \'matched\' to extremely \'mismatched\' with their recent evolutionary history."

"But Turkana who had moved to cities exhibited poor cardio-metabolic health, with much higher levels of obesity, diabetes, cardiovascular illness and high blood pressure. The health metrics also showed that the longer Turkana had spent living in the city, the less healthy they tended to be, with life-long city dwellers experiencing the greatest risk of cardiovascular disease."

1. Evolution of The Carnivore Diet [15:52]

Bradley says:

I love your podcast, I love the open minded science based approach towards diet and nutrition. \\xa0I\\u2019m a graduate of Mark Sisson\\u2019s Primal Health Coaching course and am I huge nutrition nerd. \\xa0I\\u2019ve tried vegetarian, vegan, and finally got amazing results from primal eating. \\xa0I\\u2019ve always leaned more towards the low carb mainly animal product end of the spectrum on Primal and have been listening to carnivore podcasts almost exclusively for the past few months. \\xa0I do have a comment that maybe you could help me understand. \\xa0I bought The Carnivore Code by Paul Saladino and I love the book and his points on plant self defense mechanisms and it makes sense. Maybe I missed something but if we evolved to become more animal based wouldn\\u2019t it also make sense that we\\u2019ve now evolved back to being able to eat some plants? \\xa0Maybe there hasn\\u2019t been enough time for that evolution? \\xa0Isn\\u2019t being able to drink milk without the gassy affects an evolution too though? \\xa0I appreciate any insights

https://en.wikipedia.org/wiki/Lactase_persistence#:~:text=The%20first%20identified%20genetic%20variant,C%2FT*%E2%88%9213910.&text=Other%20alleles%20associated%20with%20lactase,T%2FC*3712%20in.

2. Issues on Keto Diet: Maybe Electrolyte Imbalance? [23:53]

James says:

Hello. \\xa0My name is James and I am a 30 year old male and I live in Charlottesville, VA. \\xa0I decided to meet with a functional medicine doctor/ nutritionist about 10 weeks ago. \\xa0During my initial consultation I was at 188lbs with ~24% body fat. \\xa0I also got my blood work done that I can send for reference. \\xa0My goals are mainly focused on developing good nutrition habits to feel good and maintain a healthy body composition. \\xa0I also had consisting gas/bloating issues. \\xa0For the first 2 weeks I followed a paleo diet focused on getting adequate protein from meat sources (hand sized portion with lunch/dinner). \\xa0I also followed intermittent fasting M-F eating from 12-8. \\xa0For the next 6 weeks I practiced intermittent fasting during the week and followed a somewhat ketogenic diet ( 136g protien, 26g carbs, and 146g fat). \\xa0During this time I was also taking magnesium supplement/ fish oil at night and vitamin D/ floramyces during lunch. \\xa0I was also practicing CrossFit regularly about 5-6 times a week. \\xa0At week 6 I did a long workout in the morning in a fasted state. \\xa0Post workout I felt dizzy/weak and my legs were just cramping constantly. \\xa0I was at the point where I felt like I was going to faint. \\xa0My nutritionist said this was likely an electrolyte imbalance. \\xa0He recommended and electrolyte supplement pre/post workout and increasing magnesium on training days. \\xa0Also trying to eat low carb vegetables more to get natural sources of potassium. \\xa0I did this and I am still having some issues. \\xa0This past week I hav had some hot/cold sensations in legs/feet with some hamstring cramping. \\xa0Yesterday I was tired of this feelings and I tried eating some fruit through carbs. \\xa0This seemed to resolve my symptoms fairly quickly. \\xa0Thinking about introducing carbs back into my diet. \\xa0Right now down like 8 pounds but just want to feel a little more Normal again.

3. Weird Reaction To Beef & Lamb? [29:32]

Kim says:

Hi Nicki and Robb,

Your podcast and books are life savers. I am so, so grateful for what you do to educate! \\xa0I had been vegan/vegetarian for years but after processing the grief from suddenly losing my mom I found myself completely depleted, losing my mind, and in extreme physical pain. Through tireless research on my own over the last 3 years I have found my way to thriving health by completely changing what I eat. I believe the years as a vegan almost killed me! From this whole experience I am acutely aware of how my body reacts to different foods. I have had to eliminate all estrogenic foods but now completely enjoy my new diet based on plenty of low carb green leafy vegetables, cruciferous vegetables, some types of seeds and nuts and of course pasture raised meats and eggs and wild caught fish. My question is about a weird reaction I have to beef and lamb. When I eat fish, chicken or pork I do fine but when I eat even the highest quality grass-fed beef or lamb I have the same reaction that I do to highly estrogenic foods, anxiety and hyper awake (sleep issues). Is there anything in the amino acid profile of beef and lamb that is substantially different from that of chicken and pork that could be causing this? Is there something I could eat along with beef and lamb to counteract this reaction in my body? Ideally I would like to eat be able to eat beef and lamb over pork and chicken so I need to figure this out. Any thoughts you have would be most gratefully received.

Thank you again for all that you do.

All the best,

Kim

4. Do All Cells React to Light? [36:25]

Mariessa says:

Hi, Robb!

Regarding the blue light glasses: the book Lights Out noted that all (many? More than just eyes) cells react to the light if I\'m remembering correctly. What are your thoughts on this?

Thanks,

Mariessa

Circadian Clocks in Human Red Blood Cells

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3040566/

5. Electrolyte/Magnesium Sensitivity? [41:24]

I have found that if I have more than 1 packet of LMNT a day, I get a bit of digestive trouble probably due to the magnesium. \\xa0I seem to be fairly sensitive to magnesium in all forms. \\xa0Any tips?

Thank you for all that you do!

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