#52: Anemia: Tips, and tools for diagnosis and treatment

Published: Aug. 14, 2017, 7 a.m.

Master the anemia algorithm, and take a deep dive on iron deficiency, anemia of chronic kidney disease, anemia of chronic inflammation, causes of macrocytic anemia and more in this discussion with international expert, Dr. David P. Steensma, Senior Physician from Dana Farber Institute, and Associate Professor of Medicine at Harvard Medical School.

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Full show notes available at http://thecurbsiders.com/podcast

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Cases from Kashlak Memorial:

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  • 62 yo M with diabetes and CKD with asymptomatic Hgb 10, MCV 90, and Cr. 1.9?
  • 72 yo F with HTN with asymptomatic Hgb of 11, MCV 85 and Cr. 0.6.
  • 72 yo F with breast cancer in remission after lumpectomy, adjuvant chemo, and XRT treated 6 years ago presents with fatigue and some dyspnea on exertion. Hgb 9.6, MCV 102.
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Time Stamps

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00:00 Intro

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01:18 Listener feedback

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04:05 Announcement: We\u2019re looking for on air correspondents to join The Curbsiders

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05:05 Picks of the week

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11:12 Getting to know our guest

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17:50 Case #1 Normocytic anemia

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19:15 Defining anemia (WHO criteria)

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21:10 Epidemiology of anemia

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23:45 Normocytic anemia

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25:55 Erythropoietin for diagnosis and treatment

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28:22 Anemia of CKD or chronic inflammation?

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31:37 Discussion of ferritin and soluble transferrin receptor

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33:47 Case #1 Conclusion

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35:45 Hemoglobin targets in CKD

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36:53 Case #2 Microcytic anemia

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37:43 Correct reticulocyte count and reticulocyte index

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40:45 Deciding on dose and route for iron repletion

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43:44 Does vitamin C improve iron absorption?

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45:27 Case #3 Macrocytic anemia

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46:54 Vitamin B12 deficiency

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51:54 Medication related B12 deficiency

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52:35 Myelodysplastic syndrome

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55:00 Side effects of common MDS treatments

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56:18 Take home points

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57:35 The Curbsiders post game analysis

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64:16 Outro

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Tags: anemia, hemoglobin, i\n