#204 NephMadness 2020: SGLT2 Inhibitors

Published: April 6, 2020, 7 a.m.

Get under the hood of SGLT2 inhibitors! Listen as our guests Dr. Harish Seethapathy, Dr. Matt Sparks, and Dr. Joel Topf give us a tour through the NephMadness 2020 SGLT2i region! How do these promising drugs work, and what evidence is there for using them in non-diabetic kidney disease or kidney transplant patients. Show Notes | Spotify | Swag! | Top Picks | Mailing List | thecurbsiders@gmail.com

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\n\n\nCredits\n\n
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  • Written and Produced by: Hannah R. Abrams
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  • Cover Art and Infographic by: Hannah R. Abrams
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  • Hosts: Hannah R Abrams, Matthew Watto MD, FACP
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  • Editor: Clair Morgan of Nodderly.com (audio), Emi Okamoto MD (written)
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  • Guests: Harish Seethapathy MD; Matthew Sparks MD; Joel Topf MD
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\n\n\nSponsor: McGraw Hill\n\n
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\n\n\nTime Stamps\n\n
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  • \n00:00 Sponsor
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  • \n00:26 Intro, disclaimer, guest bio
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  • \n02:57 Guest one-liner and Picks of the Week*: Michael Pollan audiobook on Coffee and Caffeine Addiction
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  • \n03:52 SGLT2i definition, background, and why we now consider CV endpoints in diabetes
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  • \n11:16 Sponsor
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  • \n12:00 Tubuloglomerular feedback; Balloon analogy
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  • \n17:40 Other mechanisms for SGLT2i
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  • \n23:05 Back to the case; Risks from SGLT2i; Counseling and Monitoring
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  • \n34:18 SGLT2i for non-diabetic kidney disease; Possible mechanisms: Joel\u2019s caution against early adoption
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  • \n41:42 SGLT2 inhibitors in kidney transplant
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  • \n45:20 Take home points and picks for the SGLT2 inhibitor region
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  • \n49:50 Outro
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