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This presentation reviews how classic storage architectures create barriers to throughput and scaleability for several of today's hot applications. Case studies and benchmarks are used to illustrate how a very high performance, NVMe networked storage solution allows these applications to break through these barriers. Learning Objectives: 1) Understand how storage can limit scale out application performance; 2) Understand how new scale out apps apply different tiers of storage; 3) Understand barriers to application scale out; 4) Understand barriers to application throughput; 5) Understand how networked NVMe storage can dramatically improve app performance and scalability.