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Our panel discussion commemorates a momentous occasion, the 70th anniversary of the United Nations on Friday, 23rd October, the eve of \u201cUN Day\u201d that marks the entry into force of the Charter. Does multilateralism, the bedrock of the world organisation, matter in today\u2019s increasing fragmenting world? Why did it matter in 1942-45? Was the post-World War Two global order truly multilateral? In particular, what presence did the global \u2018South\u2019 have in crafting it? Our panellists are Valerie Amos, Director of SOAS and long associated with the UN and international development, Winnie Byanyima, Executive Director of Oxfam International, and Thomas Weiss, one of the most eminent scholars of international relations and the politics of the UN. They will discuss and debate the UN\u2019s role in providing the global \u2018South\u2019 an adequate platform for creating a multilateral world order in which their collective voice has been recognised\u2014both in 1945 and in 2015. The event will be introduced by Dan Plesch, Director of CISD, and Natalie Samarasinghe, Executive Director of United Nations Association UK, and chaired by the former senior UK diplomat Sir Jeremy Greenstock, best known for his chairmanship of the UN Association in the UK and extensive experience in international politics.