Cities are complex and dynamic environments, which present many opportunities for new uses of merging technologies and data. In this episode, Luis Bettencourt will address many features that are common to all cities as complex ecosystems of people interacting over the built environment. In this light, he will presesnt opportunities to make cities smarter in terms of the efficiency and quality of underlying infrastructure, as well as the creation of informational signals and better markets that can reduce transaction costs and promote connectivity and exchange. Finally, he will highlight the need for smarter cities to integrate engineering solutions with a new logic of design that incorporates open-ended human development and synergies with evolving natural environments.