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Published: Jan. 18, 2024, 7 p.m.

The longevity research world is exploding right now, it's so exciting and the technology is advancing in leaps and bounds and we are able now to discover faster than ever before thanks to AI and co to test more molecules that can impact human health than ever before in the history of mankind. What would have taken years now takes weeks or months.

In this episode I talk to Michael Antonelli CEO and founder of Healthgevity. Michael is a master formulator who has spent decades in the anti-ageing and longevity space learning at the feet of many masters and who is at the forefront of working with companies at the cutting edge in peptide and bioactive ingredient development.\xa0 \xa0 All his formulations are science backed with clinical research and I was excited to learn about something of these novel molecules like Peptistrong, Astragin, Factor 21, NAD3, Ameal Peptide and many more. \xa0 In this episode Michael walks us through some of the cutting edge molecules, what they do and how they impact various biological pathways to\xa0 hopefully improve our healthspan and lifespan. \xa0 If after listening to this episode you want to check out some of the range we now have in our shop. Click the links below: \xa0 Ignite\xa0 -Metabolic health and weightloss\xa0 Ignite+\xa0is an\xa0exclusive breakthrough formula combining the leading ingredients available to increase metabolism,\xa0improve insulin signaling, body composition, reduce uptake of glucose into our bodies, and so much more. One of the best ways to prevent insulin resistance is to help remove excess glucose from our blood. We are the first to pair these several effective glucose disposal agents together to target several vital pathways that regulate metabolic efficiency.

Ignite+\xa0is an advanced metabolic optimization formula whose ingredients have been shown to\xa0support:

• Reduction of adiposity and visceral fat*
• Increase thermogenesis by raising the metabolic rate and calorie burning*
• Browning of white adipose tissue*
• Diet-induced weight gain*
• Increase fatty acid oxidation*
• Ramp up ketone levels*
• Improves glucose tolerance and glucose control*
• AMPK activation*
• Leptin and\xa0ghrelin\xa0levels*
• Regulation of a healthy metabolism and mitochondrial health*

\xa0 Longevity\xa0 Biological aging is directly impacted by physiological integrity.\xa0Muscle strength, mass, function, quantity, and quality loss are some of the main issues associated with the process of aging. As we age the performance of our muscle cells decline which leads to a weakened immune system, sarcopenia, obesity, and chronic disease among much more. Healthgevity has selected\xa0PeptiStrong\u2122,\xa0Senactiv\xae and AstraGin\xae\xa0which are all clinically proven ingredients to put your muscles in the best position to thrive regardless of your age.

In a recent study it was concluded that lower muscle strength in late adolescence showed direct connection with higher risk of chronic disease. As such, skeletal muscle might be the central integrator between sarcopenia, obesity, immune senescence and more in an aging biological system. Preserving muscle mass is critical for optimizing health span.\xa0 Research shows the strongest one-third of the population over the age of 60 has a 50% lower death rate than the weakest, making muscle a key predictor of longevity.\xa0 Recent discoveries of clinically proven 'growth promoting' ingredients have made the process of building and preserving muscle more obtainable.\xa0

PeptiStrong\u2122,\xa0Senactiv\xae\xa0and\xa0AstraGin\xae\xa0work synergistically to target multiple mechanisms, to provide a wide range of benefits in muscle health.\xa0

CARDIO NAD+
Vascular health and aging are the most important health care problem in the world today. Healthy aging requires healthy arteries and a healthy heart. Cardio NAD+ is a state-of-the-art solution which uses the most novel ingredients available to help optimize cardiovascular health. As one of the most important systems in your body, we have designed this combination to be synergistic to the many different areas of cardiovascular health while demonstrating cardioprotective effects including the emerging connection between NAD+ and heart health.

Featured Supportive Benefits:

• Improves net NAD+ status by supporting both its synthesis and limiting its degradation
• Supports healthy blood pressure
• Improves vascular aging and endothelial function
• Supports healthy fibrinolytic activity and clotting function
• Promotes healthy circulation and blood flow
• Inhibits platelet & red blood cell aggregation
• Decreases blood viscosity
• Supports clinical measures of inflammation
• Supports healthy blood sugar and insulin levels
• Inhibits lipid peroxidation
• Supports healthy lipid metabolism
• Demonstrated reduction in various independent cardiovascular risk factors

Rejuvenate

Cellular senescence is a hallmark of aging, it is a permanent state of cell cycle arrest induced by cellular stresses.\xa0This has numerous implications for the body, including its ability\xa0to adapt to changes in its environment, as well as its capacity to regenerate itself. This\xa0can be beneficial\xa0for individuals\xa0to understand how cellular senescence\xa0works and what the potential benefits are for the body.\xa0 Firstly, understanding cellular senescence can help us better understand aging, as this process is a major contributor to the aging process.\xa0 Additionally, it can also provide insight into certain diseases and conditions that may be linked to the inability of cells to divide and proliferate\xa0properly.\xa0 Finally, by targeting cellular senescence, we\xa0may be able to find new ways of fighting against\xa0aging and diseases associated with it.\xa0 Thus, understanding\xa0ways to best support cellular senescence\xa0can be a powerful tool in our pursuit of longevity and improved health span.\xa0\xa0Senolytics, are\xa0small molecules that can selectively kill senescence cells and have been developed to support various age-related diseases while also\xa0extending healthspan. In recent years, emerging natural compounds have been discovered to be effective senolytic agents that are featured in this breakthrough formula. Clearance of senescent cells can support the reduction of inflammation, decrease macromolecular dysregulation, and enhance function of stem and progenitor cells.

Rejuvenate\xa0presents a unique solution\xa0for intervention through two mechanisms:\xa0

(1) eliminating senescent cells (senolytics)\xa0

\xa0(2) inhibiting of senescent- associated secretory phenotype (SASP)\xa0

Featured benefits:\xa0

• Once weekly pulsed high dosing blend of\xa0senolytics\xa0which have been shown to reduce senescent cells in vivo.
• Targets aging at the cellular level
• Induces autophagy to promote intracellular recycling and cellular renewal
• Reduce full body features of Senescence-Associated Secretory Phenotype (SASP).
• Protects cells against free radicals and oxidative stress\xa0
• Targets inflammaging at the cellular level and supports a healthy inflammatory response
• Supports a healthy immune system\xa0
• Formula designed to also treat muscle senescence.
• Exercises muscles longer and harder with a boost in citrate synthase activity.
• Recovers more effectively with a reduction in inflammation biomarkers.
• Decreases SA-\u03b2-Gal by 63% in muscle tissue.

\xa0 \xa0 For more information on Michael and Healthgevity\xa0you can also go to\xa0www.healthgev.com \xa0 BIO

Throughout a career spanning over 17 years, Michael passionately devoted himself to pioneering methods aimed at enhancing longevity, optimizing healthspan, and elevating overall quality of life. His focus revolves around collaborating with leading healthcare professionals, researchers, and other likeminded healthcare leaders to create natural solutions that elevate patient outcomes.\xa0

Michael utilizes his past experiences that integrates a diverse range of therapies and services, spanning from precision diagnostics to practice management strategies, hormone optimization, nutritional supplements, and leveraging peptides. Previous roles included Chief Innovation Officer, Executive Director, and Business Development for leading companies within the healthcare industry before founding Healthgevity. His expertise extends beyond conventional approaches, emphasizing holistic well-being and personalized care as essential components to any successful medical practice.\xa0

By championing novel methodologies and innovative technologies, Michal facilitates transformative changes within the healthcare landscape, fostering advancements that positively impact both practitioners and the individuals they serve.\xa0 Michael continues to remain dedicated to the pursuit of innovative strategies that enhance health and vitality while reshaping the paradigms of healthcare.

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Personalised Health Optimisation Consulting with Lisa Tamati

Lisa offers solution focused coaching sessions to help you find the right answers to your challenges.

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Topics Lisa can help with:\xa0

Lisa is a Genetics Practitioner, Health Optimisation Coach, High Performance and Mindset Coach.

She is a qualified Ph360 Epigenetics coach and a clinician with The DNA Company and has done years of research into brain rehabilitation, neurodegenerative diseases and biohacking.

She has extensive knowledge on such therapies as hyperbaric oxygen,\xa0 intravenous vitamin C, sports performance, functional genomics, Thyroid, Hormones, Cancer and much more. She can assist with all functional medicine testing.

Testing Options

• Comprehensive Thyroid testing

• DUTCH Hormone testing

• Adrenal Testing

• Organic Acid Testing

• Microbiome Testing

• Cell Blueprint Testing

• Epigenetics Testing

• DNA testing

• Basic Blood Test analysis

• Heavy Metals\xa0

• Nutristat

• Omega 3 to 6 status

and more\xa0

Lisa and her functional medicine colleagues in the practice can help you navigate the confusing world of health and medicine .

She can also advise on the latest research and where to get help if mainstream medicine hasn't got the answers you are searching for whatever the\xa0 challenge you are facing from cancer to gut issues, from depression and anxiety, weight loss issues, from head injuries to burn out to hormone optimisation to the latest in longevity science.\xa0Book your consultation with Lisa\xa0

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Please join our patron community and get exclusive member benefits (more to roll out later this year) and support this educational platform for the price of a coffee or two

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Lisa\u2019s Anti-Aging and Longevity Supplements\xa0

Lisa has spent years curating a very specialized range of exclusive longevity, health optimizing supplements from leading scientists, researchers and companies all around the world.\xa0

This is an unprecedented collection. The stuff Lisa wanted for her family but couldn't get in NZ that\u2019s what it\u2019s in her range. Lisa is constantly researching and interviewing the top scientists and researchers in the world to get you the best cutting edge supplements to optimize your life.

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Order Lisa's Books

Lisa has published 5 books: Running Hot, Running to Extremes, Relentless, What your oncologist isn't telling you and her latest "Thriving on the Edge"\xa0

Check them all out at\xa0

https://shop.lisatamati.com/collections/books

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Perfect Amino Supplement by Dr David Minkoff

Introducing PerfectAmino

• PerfectAmino is an amino acid supplement that is 99% utilized by the body to make protein.

• PerfectAmino is 3-6x the protein of other sources with almost no calories.

• 100% vegan and non-GMO.

• The coated PerfectAmino tablets are a slightly different shape and have a natural, non-GMO, certified organic vegan coating on them so they will glide down your throat easily.

• Fully absorbed within 20-30 minutes!

• No other form of protein comes close to\xa0PerfectAminos

Listen to the episode with\xa0Dr Minkoff here:\xa0

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Use code "tamati" at checkout to get a 10% discount on any of their devices.

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Red Light Therapy:

Lisa is a huge fan of Red Light Therapy and runs a Hyperbaric and Red Light Therapy clinic. If you are wanting to get the best products try

Flexbeam: A wearable Red Light Device

https://recharge.health/product/flexbeam-aff/?ref=A9svb6YLz79r38

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To find out more about photobiomodulation, current studies underway and already completed and for the devices mentioned in this video go to

www.vielight.com\xa0and use code \u201ctamati\u201d to get 10% off

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To pushing the limits,

Lisa and team