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I have become hooked on playing online chess during this lockdown and after watching the Queen\u2019s Gambit. So we\u2019ll find out if it is actually doing my brain any good and whether it and similar games can ward off dementia.

Margaret McCartney takes us on a fascinating tour through the history of deliberately infecting people with diseases, as the first \u201cchallenge trials\u201d with coronavirus are about to start.

Listeners David and Barbara tell us about a treatable condition called normal pressure hydrocephalus that is often mistaken for dementia.

PRESENTER: James Gallagher\nPRODUCER: Beth Eastwood

Clip from the Netflix series 'The Queen's Gambit', directed by Scott Frank. \nMusic copyright: \u2018Training with Mr Schaibel\u2019 by Carolos Rafael Rivera from the official soundtrack of The Queens Gambit