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Proverbs 3:5-6 "Trust in the LORD with all your heart; and lean not on your own understanding. In all your ways acknowledge him, and he shall direct your paths." 

We are told, positively, to trust the Lord and, negatively, not to trust our own understanding. Those two things are mutually exclusive. In other words, if we trust in the Lord, we cannot also depend upon our own ability to understand everything God is doing.

Most of us have a desperate desire to understand, but in so many areas we must acknowledge that we cannot understand. We must approve of God’s ways, even when we can’t comprehend them. Isaiah 55:8-9 tells us why we often don’t understand what God is doing: "'For my thoughts are not your thoughts, neither are your ways my ways,' declares the Lord. 'For as the heavens are higher than the earth, so are my ways higher than your ways and my thoughts than your thoughts.'" 

God sees the whole picture, while we only see our tiny corner of it. To trust in the Lord with all our heart means we can’t place our own right to understand above His right to direct our lives the way He sees fit. When we insist that we must understand what  God is doing for us to embrace or go along with it  we are setting ourselves up for spiritual, emotional, financial and physical trouble.

Our limited understanding can easily lead us astray. Proverbs 16:25 says, "There is a way that appears to be right, but in the end it leads to death." When we choose to direct our lives according to what seems right to us, we often reap disaster (Judges 21:25). Every culture has tried to get God to approve of its definition of right and wrong, but God never changes and His standards never change

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