In this episode, I discuss fear and trauma, including the neural circuits involved in the "threat reflex" and how specific experiences and memories come to activate that system. I also discuss how our body is involved in trauma and fear. First, I describe the logic of fear mechanisms and how "top-down" processing-- meaning connections from the parts of the brain that assign meaning to our feelings, are involved in fear and erasing fears and traumas. Then I discuss what successful fear and trauma treatment must include and consider various treatments for whether they meet that standard, such as EMDR, Cognitive Behavioral Therapy, Ketamine, other drug-assisted therapies, and more. I also review new data on how 5 minutes per day of deliberate, self-imposed stress can erase fear and depression. And I review the role that social connection plays in erasing or maintaining fears by activating specific molecular pathways in the brain and body. Finally, I review supplementation with over-the-counter compounds for their effects on anxiety and fear and when to take them, if at all.\xa0\nFor the full show notes, visit hubermanlab.com.\nThank you to our sponsors\nAG1 (Athletic Greens): https://athleticgreens.com/huberman\nLMNT: https://drinklmnt.com/huberman\nSupplements from Momentous\nhttps://www.livemomentous.com/huberman\nTimestamps\n(00:00:00) Introducing Fear, Trauma & Trauma\xa0\n(00:02:31) Sponsors: AG1, LMNT\n(00:06:49) What is Fear?\xa0\n(00:11:45) Autonomic Arousal: \u201cAlertness\u201d vs. \u201cCalmness\u201d\n(00:13:44) Hypothalamic-Pituitary-Adrenal Axis (HPA axis)\n(00:17:36) \u201cThe Threat Reflex\u201d: Neural Circuits for Fear\n(00:28:24) Controlling Fear: Top-Down Processing\n(00:32:27) Narratives: \u201cProtective or Dangerous\u201d\n(00:35:58) Attaching Fear to Events: Classical Conditioning & Memory\n(00:41:45) How Fear Learning Occurs: Long Term Potentiation, NMDA\n(00:46:10) Extinguishing (Reducing) Fears\n(00:50:25) Cognitive (Narrative) Therapies for Fear\n(00:57:56) Repetition of Narrative, Overwriting Bad Experiences with Good\n(01:05:28) EMDR: Eye Movement Desensitization Reprocessing\n(01:14:00) Social Connection & Isolation Are Chemically Powerful\n(01:18:23) Trans-Generational Trauma\n(01:25:00) PTSD Treatments: Ketamine, MDMA, oxytocin\n(01:39:25) How Do You Know If You Are Traumatized?\xa0\n(01:46:16) Deliberate Brief Stress Can Erase Fears & Trauma\n(01:49:50) Erasing Fears & Traumas In 5 Minutes Per Day\n(01:59:42) Nutrition, Sleep, & Other General Support Erasing Fear & Trauma\n(02:02:30) Supplements for Anxiety, Fear: Saffron, Inositol, Kava\n(02:10:00) Synthesis\xa0\n(02:11:46) Zero-Cost Support, Sponsors, Supplements, Instagram, Twitter\nTitle Card Photo Credit: Mike Blabac\nDisclaimer