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In this episode of the Epigenetics Podcast, we caught up with Elena Gomez-Diaz from the Institute of Parasitology and Biomedicine L\xf3pez-Neyra at the Spanish National Research Council. She share with us her work on the Epigenetics in Human Malaria Parasites.\nElena G\xf3mez-D\xedaz and her team are focusing on understanding how epigenetic processes are implicated in host-parasite interactions by regulating gene expression in the model of malaria. The team has started to investigate and uncover layers of chromatin regulation that control developmental transitions in Plasmodium falciparum, especially in the parts of the life cycle that take place in the mosquito. Furthermore, the lab has investigated epigenetic changes that are present in malaria-infected Anopheles mosquitos, this led to the identification of cis-regulatory elements and enhancer-promoter networks in response to infection.\n\xa0\nReferences\n\nG\xf3mez-D\xedaz E, Rivero A, Chandre F, Corces VG. Insights into the epigenomic landscape of the human malaria vector Anopheles gambiae. Front Genet. 2014 Aug 15;5:277. doi: 10.3389/fgene.2014.00277. PMID: 25177345; PMCID: PMC4133732.\n\n\nG\xf3mez-D\xedaz, E., Yerbanga, R., Lef\xe8vre, T. et al. Epigenetic regulation of Plasmodium falciparum clonally variant gene expression during development in Anopheles gambiae. Sci Rep 7, 40655 (2017). https://doi.org/10.1038/srep40655\n\n\nJos\xe9 Luis Ruiz, Juan J Tena, Cristina Bancells, Alfred Cort\xe9s, Jos\xe9 Luis G\xf3mez-Skarmeta, Elena G\xf3mez-D\xedaz, Characterization of the accessible genome in the human malaria parasite. Plasmodium falciparum, Nucleic Acids Research, Volume 46, Issue 18, 12 October 2018, Pages 9414\u20139431, https://doi.org/10.1093/nar/gky643\n\n\nWomen in Malaria 2021: A Conference Premier. (2021). Trends in Parasitology, 37(7), 573\u2013580. https://doi.org/10.1016/j.pt.2021.04.001\n\nTwitter Account: https://twitter.com/womeninmalaria\n\n\xa0\n\nRelated Episodes\n\nMultiple challenges of CUT&Tag (Cassidee McDonough, Kyle Tanguay)\n\n\nATAC-Seq, scATAC-Seq and Chromatin Dynamics in Single-Cells (Jason Buenrostro)\n\n\xa0\nContact\n\nEpigenetics Podcast on Twitter\n\n\nEpigenetics Podcast on Instagram\n\n\nEpigenetics Podcast on Mastodon\n\n\nActive Motif on Twitter\n\n\nActive Motif on LinkedIn\n\n\nEmail: podcast@activemotif.com