Podcasts Health EM Clerkship Thrombocytopenia

Thrombocytopenia

Published: March 11, 2018, 9 a.m.

Clinical Presentation Incidental finding on routing CBC Petechiae/purpura Mucosal bleeding Epistaxis Gingival bleeding Hematuria Vaginal bleeding 5 Major Causes of Thrombocytopenia Thrombotic Thrombocytopenic Purpura (TTP) Clinical presentation (pentad) Thrombocytopenia Fever Microangiopathic hemolytic anemia \u201cschistocytes\u201d Neurologic abnormalities Renal dysfunction Physiology Low ADAMTS13 results in impaired vWF breakdown Widespread \u201cplatelet plugs\u201d Treatment Plasma exchange Hemolytic Uremic Syndrome [\u2026]