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How do you counsel patients on beta blockers? Is one beta-blocker better than the other? What is preferred: ACEi, ARBs or ARNIs? What are the pros and cons of each? How does spironolactone compare to eplerenone? When do you stop mineralocorticoid receptor antagonist? What are risks with SGLT2 inhibitors? How do you initiate GDMT? Which meds do you start first and in what order?Show notes, Transcript and References:\xa0\xa0https://www.coreimpodcast.com/2022/05/11/5-pearls-on-guideline-directed-medical-therapy/Sponsor: https://go.amboss.com/GDMT (https://go.amboss.com/GDMT)Get CME-MOC credit with ACP: https://www.acponline.org/cme-moc/cme/internal-medicine-podcasts/core-im\xa0Time stamps:* 03:13 Pearl 1* 12:14 Pearl 2* 20:36 Pearl 3* 26:42 Pearl 4* 32:16 Pearl 5Tags: IM Core, CoreIM, heart failure with reduced ejection fraction, GDMT, treatment, cardiology\n\nFind the best disability insurance for you: https://www.patternlife.com/disability-insurance?campid=497840\n\nAdvertising Inquiries: https://redcircle.com/brands\n\nPrivacy & Opt-Out: https://redcircle.com/privacy