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Molluscan dorsal-ventral patterning relying on BMP24 and Chordin provides insights into spiralian development and bilaterian body plan evolution

Published: Aug. 14, 2020, 5:02 p.m.
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Listed in: Science

Timed mesodermal FGF and BMP govern the multi-step thyroid specification

Published: Aug. 13, 2020, 7:02 p.m.
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Listed in: Science

Regulated delivery controls Drosophila Hedgehog, Wingless and Decapentaplegic signaling

Published: Aug. 13, 2020, 10:03 a.m.
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Listed in: Science

FGF signaling induces mesoderm in members of Spiralia

Published: Aug. 13, 2020, 8:01 a.m.
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Listed in: Science

PTEN Inhibition Ameliorates Muscle Degeneration and Improves Muscle Function in a Mouse Model of Duchenne Muscular Dystrophy

Published: Aug. 13, 2020, 6:01 a.m.
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Listed in: Science

A Wnt-specific astacin proteinase controls head formation in Hydra

Published: Aug. 13, 2020, 6:01 a.m.
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WntPCP-primed intestinal stem cells directly differentiate into enteroendocrine or Paneth cells

Published: Aug. 12, 2020, 11:01 p.m.
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Listed in: Science

Postembryonic screen for mutations affecting spine development in zebrafish

Published: Aug. 12, 2020, 8:01 a.m.
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Endothelial Cell Cycle State Determines Propensity for Arterial-Venous Fate

Published: Aug. 12, 2020, 2:06 a.m.
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Myogenin is an Essential Regulator of Adult Myofibre Growth and Muscle Stem Cell Homeostasis

Published: Aug. 10, 2020, 11:01 p.m.
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PU.1 drives specification of pluripotent stem cell-derived endothelial cells to LSEC-like cells

Published: Aug. 10, 2020, 1:03 p.m.
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The intrinsically disordered protein SPE-18 promotes localized assembly of the major sperm protein in C. elegans spermatocytes

Published: Aug. 10, 2020, 1:02 p.m.
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Identification of limb-specific Lmx1b auto-regulatory modules with Nail-Patella Syndrome pathogenicity.

Published: Aug. 10, 2020, 1:02 p.m.
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Listed in: Science

Dach1 extends artery networks and protects against cardiac injury

Published: Aug. 10, 2020, 1:02 p.m.
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Listed in: Science

The tolerance to hypoxia is defined by a time-sensitive response of the gene regulatory network in sea urchin embryos

Published: Aug. 10, 2020, 1:02 p.m.
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Ciona Brachyury proximal and distal enhancers have different FGF dose-response relationships

Published: Aug. 7, 2020, 5:01 a.m.
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Specification and epigenetic resetting of the pig germline exhibit conservation with the human lineage

Published: Aug. 7, 2020, 12:05 a.m.
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Adipose tissue developmental growth constraints uncouple fat distribution from glucose metabolism in two mouse models of obesity

Published: Aug. 7, 2020, 12:05 a.m.
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Impaired Fetal Lung Development can be Rescued by Administration of Extracellular Vesicles Derived from Amniotic Fluid Stem Cells

Published: Aug. 7, 2020, 12:05 a.m.
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Epigenetic change induced by in utero dietary challenge provokes phenotypic variability across multiple generations of mice

Published: Aug. 7, 2020, 12:05 a.m.
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Systematic comparison of developmental GRNs explains how novelty is incorporated in early development

Published: Aug. 7, 2020, 12:05 a.m.
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Bacterial symbionts in animal development: arginine biosynthesis complementation enables larval settlement in a marine sponge

Published: Aug. 7, 2020, 12:05 a.m.
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Tracking H3K27me3 and H4K20me1 dynamics during XCI reveals similarities in recruitment mechanism

Published: Aug. 6, 2020, 6:02 p.m.
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SNPC-1.3 is a sex-specific transcription factor that drives male piRNA expression in C. elegans

Published: Aug. 6, 2020, 7:03 a.m.
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Listed in: Science

Quantitative lineage analysis identifies a long-term progenitor niche for the hepato-pancreato-biliary organ system

Published: Aug. 6, 2020, 6:01 a.m.
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Induction of Ventral Spinal V0 Interneurons from Mouse Embryonic Stem Cells

Published: Aug. 6, 2020, 5:03 a.m.
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Listed in: Science

The microtubule organization in the zebrafish yolk adapts to transgene-mediated phenotypic variations

Published: Aug. 6, 2020, 5:03 a.m.
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Listed in: Science

Single-cell analyses of the corneal epithelium: Unique cell types and gene expression profiles

Published: Aug. 6, 2020, 5:03 a.m.
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Pregnancy success in mice requires appropriate cannabinoid receptor signaling for primary decidua formation

Published: Aug. 5, 2020, 11:02 p.m.
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Impairment of the Hif-1α regulatory pathway in Foxn1-deficient (Foxn1--) mice affects the skin wound healing process

Published: Aug. 5, 2020, 6:02 a.m.
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Listed in: Science

Effects of Starter Feeds of Different Physical Forms on Rumen Fermentation and Microbial Composition for Pre-weaning and Post-weaning Lambs

Published: Aug. 4, 2020, 11:01 p.m.
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Listed in: Science

An unexpected bifurcation in the Pointed transcriptional effector network contributes specificity and robustness to retinal cell fate acquisition

Published: Aug. 4, 2020, 9:02 a.m.
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An immobilization technique for long-term time-lapse imaging of explanted Drosophila tissues

Published: Aug. 4, 2020, 6:01 a.m.
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Listed in: Science

A transitory signaling center controls timing of primordial germ cell differentiation

Published: Aug. 3, 2020, 4:02 p.m.
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A Unified Framework for Lineage Tracing and Trajectory Inference

Published: Aug. 3, 2020, 4:02 p.m.
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Sequential onset and concurrent expression of miR-9 genomic loci in single cells contributes to the temporal increase of mature miR-9 in zebrafish neurogenesis

Published: Aug. 3, 2020, 4:02 p.m.
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Listed in: Science

Maternal iron deficiency perturbs embryonic cardiovascular development

Published: Aug. 3, 2020, 9:02 a.m.
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Listed in: Science

Twisting of the heart tube during cardiac looping is a tbx5-dependent and tissue-intrinsic process

Published: Aug. 3, 2020, 9:02 a.m.
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Listed in: Science

A dynamic and spatially periodic micro-pattern of HES5 expression underlies the probability of neuronal differentiation in the mouse spinal cord

Published: Aug. 3, 2020, 8:02 a.m.
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Developmental Incongruity as a Dynamical Representation of Heterochrony

Published: Aug. 2, 2020, 1:01 p.m.
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Multifaceted functions of Rab23 on primary cilium and Hedgehog signaling-mediated granule cell proliferation

Published: Aug. 1, 2020, 8:01 a.m.
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Notch-Directed Germ Cell Proliferation Is Mediated by Proteoglycan-Dependent Transcription

Published: July 31, 2020, 11:01 p.m.
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Retracing Schwann cell developmental transitions in embryonic dissociated DRG cultures

Published: July 31, 2020, 4:01 a.m.
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Three-Component Model of the Spinal Nerve Branching Pattern, based on the View of the Lateral Somitic Frontier and Experimental Validation

Published: July 30, 2020, 5:02 p.m.
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Application of CRISPRCas9 nuclease in amphioxus genome editing

Published: July 30, 2020, 10:02 a.m.
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Circadian timing-dependent myoblast differentiation and muscle regeneration

Published: July 30, 2020, 9:02 a.m.
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Cullin3 promotes stem cell progeny differentiation by facilitating aPKC-directed asymmetric Numb localization

Published: July 29, 2020, 8:02 a.m.
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Pdgfra and Pdgfrb genetically interact in the murine neural crest cell lineage to regulate migration and proliferation

Published: July 29, 2020, 6:01 a.m.
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ERβ regulated ovarian kisspeptin plays an important role in oocyte maturation

Published: July 29, 2020, 3:01 a.m.
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Low Dose Lead Exposure Induces Alterations on Heterochromatin Hallmarks Persisting Through SH-SY5Y Cell Differentiation

Published: July 29, 2020, 2:03 a.m.
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Listed in: Science

Dense reconstruction of elongated cell lineages: overcoming suboptimum lineage encoding and sparse cell sampling

Published: July 29, 2020, 1:04 a.m.
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3D MAPs discovers the morphological sequence chondrocytes undergo in the growth plate and the regulatory role of GDF5 in this process

Published: July 28, 2020, 9:01 a.m.
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Listed in: Science

Single cell visualisation of mir-9a and Senseless co-expression during Drosophila melanogaster embryonic and larval peripheral nervous system development

Published: July 28, 2020, 5:01 a.m.
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The Drosophila MOZ homolog Enok controls Notch-dependent induction of the RUNX gene lozenge independently of its histone-acetyl transferase activity.

Published: July 28, 2020, 1:01 a.m.
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Listed in: Science

Endocardialendothelial angiocrines regulate cardiomyocyte development and maturation and induce features of ventricular non-compaction

Published: July 26, 2020, 7:37 p.m.
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Listed in: Science

Expression of Wnt5a defines the major progenitors of fetal and adult Leydig cells

Published: July 26, 2020, 7:37 p.m.
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Cytokinetic abscission is part of the mid-blastula transition switch in early zebrafish embryogenesis

Published: July 26, 2020, 7:37 p.m.
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The direct regulation of Aalbdsx on AalVgR is Indispensable for ovarian development in Aedes albopictus

Published: July 26, 2020, 7:37 p.m.
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Differential activation of JAK-STAT signaling in blood cell progenitors reveals functional compartmentalization of the Drosophila lymph gland.

Published: July 26, 2020, 7:36 p.m.
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Interplay between medial nuclear stalling and lateral cellular flow underlies cochlear duct morphogenesis

Published: July 25, 2020, 7:37 p.m.
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Gradual centriole maturation associates with the mitotic surveillance pathway in mouse development

Published: July 25, 2020, 7:37 p.m.
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Programmed cell senescence in the mouse developing spinal cord and notochord

Published: July 25, 2020, 7:37 p.m.
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Epidermal stratification is uncoupled from centrosome-dependent cell division orientation of the basal progenitors

Published: July 25, 2020, 7:34 p.m.
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An organoid and multi-organ developmental cell atlas reveals multilineage fate specification in the human intestine

Published: July 25, 2020, 7:34 p.m.
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Incoherent feedforward regulation via Sox9 and Erk underpins mouse tracheal cartilage development

Published: July 24, 2020, 7:34 p.m.
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The effect of absent blood flow on the zebrafish cerebral and trunk vasculature

Published: July 24, 2020, 7:34 p.m.
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An atlas of lamina-associated chromatin across thirteen human cell types reveals cell-type-specific and multiple subtypes of peripheral heterochromatin

Published: July 24, 2020, 7:34 p.m.
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Genotypic Complexity in Initial Cleavage Divisions of Mammalian Embryos is Contributed by Defective BUB1BBUBR1 Signaling

Published: July 24, 2020, 7:34 p.m.
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The BMP antagonist Gremlin1 contributes to the development of cortical excitatory neurons, motor balance and fear responses

Published: July 24, 2020, 7:34 p.m.
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Sensitivity to perturbations of a cell migration under temporal regulation

Published: July 23, 2020, 7:34 p.m.
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Segmentation of the Zebrafish Brain Vasculature from Light Sheet Fluorescence Microscopy Datasets

Published: July 22, 2020, 7:35 p.m.
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Drosophila p53 isoforms have overlapping and distinct functions in germline genome integrity and oocyte quality control.

Published: July 22, 2020, 7:35 p.m.
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Neonatal hyperoxia enhances age-dependent expression of SARS-CoV-2 receptors in mice

Published: July 22, 2020, 7:34 p.m.
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BMP signalling directs a fibroblast-to-myoblast conversion at the connective tissuemuscle interface to pattern limb muscles

Published: July 21, 2020, 7:35 p.m.
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A spatially resolved single cell atlas of human gastrulation

Published: July 21, 2020, 7:35 p.m.
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Fibroblast fusion to the muscle fiber regulates myotendinous junction formation

Published: July 21, 2020, 7:35 p.m.
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Overlapping and non-overlapping roles of the class-I histone deacetylase-1 corepressors, LET-418, SIN-3, and SPR-1 in Caenorhabditis elegans embryonic development

Published: July 21, 2020, 7:35 p.m.
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Listed in: Science

CAMSAP3 is required for mTORC1-dependent ependymal cell growth and lateral ventricle shaping in mouse brains

Published: July 20, 2020, 7:35 p.m.
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Variability of an early developmental cell population underlies stochastic laterality defects

Published: July 20, 2020, 7:35 p.m.
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Muscle cell type diversification driven by extensive gene duplications

Published: July 19, 2020, 7:35 p.m.
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Listed in: Science