What is Pregnenolone Used For? | PYHP 035

Published: Feb. 15, 2018, 12:45 a.m.

b'What is pregnenolone? It is a steroid hormone but is not a reproductive hormone like estrogen or testosterone.\\xa0 Pregnenolone is also made from cholesterol, which makes it a steroid hormone.\\xa0It is also considered to be a pro-hormone,\\u2019 because it can convert into other hormones depending on the needs of the body. Recently, it has been discovered that pregnenolone is also produced in the brain and spinal cord, which makes it very potent on stimulating the central nervous system and having an impact on the brain.\\nPregnenolone is helpful for memory. It is stimulating to the brain for memory and learning, but at the same time, it is also neuroprotective. \\xa0The brain is very complicated, and pages could be written on the process of memory foundation and degradation. What we are trying to say here is, pregnenolone helps with learning and also preserving memory by protecting brain cells.\\nOther helpful uses for pregnenolone:\\n\\n\\nMemory: short-term\\nBrain fog\\nMental energy and mental motivation\\nHelpful for learning new information\\nMood \\nFocus\\n\\nPregnenolone, like most hormones declines with age. However, pregnenolone can also drop in response to high levels of chronic stress. \\xa0Whether that stress is mentally induced such as dealing with a family member's illness, PTSD or a stressful high paced life. Or physical stress such as intense daily cardiovascular exercise can diminish levels of pregnenolone. \\xa0\\nThis is also known as \\u2018pregnenolone-steal.\\u2019 \\xa0In times of chronic stress, the body will shunt the production away from the other steroid hormones to produce more cortisol. \\xa0For women, the body will shunt production away from progesterone to make more cortisol. \\xa0\\nYou can test for pregnenolone levels in the blood, but the lab reference ranges are so vast that most everyone will fall in normal ranges. \\xa0Quest has a reference range of 22-237 ng/dL, and LabCorp\\u2019s is anything less than 151 ng/dL. \\nBoth are broad reference ranges. I like to see pregnenolone 80-100. \\xa0If a pregnenolone blood test is less than 80 ng/ dL, I will treat the patient with pregnenolone. \\xa0And after being on the pregnenolone for 1-3 months, I will retest the blood work to see where their levels are and how they are feeling. \\xa0\\nAs we all know, too much of a good thing' is not-so-good. \\xa0Taking too much pregnenolone can have side effects. \\xa0There is not a lot of research on pregnenolone. \\xa0There are some animal studies but not any real prolific human studies. For the layperson, there is not a lot of information about pregnenolone online. There are some contradictory statements on dosing, side effects, and safety. \\n\\nWhat I can tell you from my experience with patients, there are relatively little side effects with pregnenolone, as long as you keep the dosage uniquely prescribed for the patient based on their symptoms and the blood work readings. \\xa0\\nPregnenolone is available over the counter/online without a prescription. \\xa0Many pregnenolone doses are just way too high. \\xa0I have had new patients walk into my office, and they are on 100mg or more of pregnenolone per day. \\xa0There are a few exceptions based on'