Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2020.07.29.227454v1?rss=1 Authors: Tung, H.-R., Durrett, R. Abstract: We investigate the site frequency spectrum in the two-type model of clonal evolution. If the fitnesses of the two types are {lambda}_0<{lambda}_1 then the site frequency spectrum is c/f^ where ={lambda}_0/{lambda}_1. This is due to the advantageous mutations that produce the founders of the type 1 population. Mutations within the growing type 0 and type 1 populations follow the 1/f law. Our results show that neutral evolution can be distinguished from the two-type model using the site frequency spectrum. Copy rights belong to original authors. Visit the link for more info