What the Phage: A scalable workflow for the identification and analysis of phage sequences

Published: July 25, 2020, 8:59 p.m.

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2020.07.24.219899v1?rss=1 Authors: Marquet, M., HoĢˆlzer, M., Pletz, M. W., Viehweger, A., Makarewicz, O., Ehricht, R., Brandt, C. Abstract: Phages are among the most abundant and diverse biological entities on earth. Identification from sequence data is a crucial first step to understand their impact on the environment. A variety of bacteriophage identification tools have been developed over the years. They differ in algorithmic approach, results and ease of use. We, therefore, developed 'What the Phage' (WtP), an easy-to-use and parallel multitool approach for phage identification combined with an annotation and classification downstream strategy, thus, supporting the user's decision-making process when the phage identification tools are not in agreement to each other. WtP is reproducible and scales to thousands of datasets through the use of a workflow manager (Nextflow). WtP is freely available under a GPL-3.0 license (https://github.com/replikation/What_the_Phage). Copy rights belong to original authors. Visit the link for more info