Recovering genomes and phenotypes using allele-specific gene expression

Published: Nov. 12, 2020, 12:01 a.m.

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2020.11.11.377978v1?rss=1 Authors: Gursoy, G., Lu, N., Wagner, S., Gerstein, M. Abstract: With the recent increase in RNA sequencing efforts using large cohorts of individuals, studying allele-specific gene expression is becoming increasingly important. Here, we report that, despite not containing explicit variant information, a list of allele-specific gene names of an individual is enough to recover key variants and link the individual back to their genome or phenotype. This creates a privacy conundrum. Copy rights belong to original authors. Visit the link for more info